Controlled molecular level motion is being used in a number of key natural processes which suggests that it could help in bridging the vacuum between the present generation of synthetic molecular systems which generally rely on electronic and chemical effects for carrying out their functions. Molecular level machines relate back to the period when ideas surrounding laws of thermodynamics were being formulated. Researchers have figured out a way for taming molecular level movement and the progress which has been made with regards to utilization of synthetic molecular structures for performing tasks with regards to mechanical motion. Though this can be achieved but still there are a number of challenges and issues which need to be sorted out. Let’s see how much nanotechnology can contribute to it.